结肠息肉与代谢综合征的相关研究进展

Research progress on correlation on colonic polyps and metabolic syndrome

结肠息肉指肠腔黏膜表面向肠腔突出的一类赘生物的统称。代谢综合征(MS)是由肥胖、高血糖、高血压及血脂异常等集结发病的一组临床症候群。目前,多项研究表明,结肠息肉的发生、发展与MS密切相关。结肠息肉经各种物理、化学、肠道微生物及心理等影响因素刺激,大部分可发展成结肠腺瘤,是结肠癌的癌前病变,可进一步发展为结肠癌。回顾性分析结肠息肉与MS的相关性发现,控制结肠息肉发生、发展的相关因素是降低息肉发生及癌变的关键。该文对结肠息肉与MS的相关性研究进展进行了综述,以期通过控制影响结肠息肉发生、发展的相关因素降低其发生率及癌变率。

Colonic polyps refers to a kind of neoplasm protruding from the mucosal surface of the intestinal cavity.Metabolic syndrome(MS)is a group of clinical syndromes associated with obesity,hyperglycemia,hypertension and dyslipidemia.At present,many studies have shown that the occurrence and development of colonic polyps are closely related to MS.Colonic polyps are stimulated by various physical,chemical,intestinal microbial and psychological factors,and most of them can develop into colorectal adenomas,which are precancerous lesions of colon cancer and can further develop into colon cancer.The retrospective analysis of the correlation between colonic polyps and MS showed that controlling the factors related to the occurrence and development of colonic polyps is the key to reduce the occurrence and cancerization of colonic polyps.This article reviews the research progress of the correlation between colonic polyps and MS,in order to reduce the incidence and the canceration rate of colonic polyps by controlling the related factors affecting the occurrence and development of colonic polyps.