慢性肾脏病合并非瓣膜性心房颤动患者抗凝管理的专家共识

Expert consensus on anticoagulation management in chronic kidney disease patients complicated with non-valvular atrial fibrillation

慢性肾脏病合并非瓣膜性心房颤动患者存在血栓栓塞类疾病、出血发生率高等特点,此类患者抗凝治疗是肾脏科医生和心脏科医生的难点。基于当前诊疗现状,本专家共识由肾脏病、心脏病、药学专家组成的编写委员会共同编写,结合循证医学证据及临床使用经验,系统介绍了慢性肾脏病合并非瓣膜性心房颤动患者血栓栓塞风险及出血风险评估、抗凝时机及用药选择等。目的在于指导、规范慢性肾脏病合并非瓣膜性心房颤动患者抗凝治疗,提高临床诊疗水平。

The incidence of thromboembolic diseases and hemorrhage is high in chronic kidney disease(CKD)patients complicated with non-valvular atrial fibrillation.Nephrologists and cardiologists are facing problems in anticoagulation treatment for these patients.A committee composed of nephrologists,cardiologists and pharmaceutical experts compiled the consensus based on current status of clinical diagnosis and treatment of the disease.According to the data of evidence-based medicine and clinical experiences,this consensus systematically introduces the risk assessment of thromboembolism and bleeding,the timing of starting anticoagulant therapy and the drug of choice,in order to guide and standardize the anticoagulant treatment and to improve clinical diagnosis and treatment of non-valvular atrial fibrillation in CKD patients.