肠易激综合征疼痛治疗现状和进展

Status and Progress of Pain Treatment in Irritable Bowel Syndrome

腹痛是肠易激综合征(IBS)患者突出的临床症状,极大影响患者的生命质量。由于其病因的复杂性以及存在的巨大个体差异,处理IBS患者的腹痛仍是临床难点。近年针对IBS腹痛的治疗方法主要包括非药物治疗(饮食、运动等生活方式干预、肠道微生态调节)、药物疗法(解痉药、薄荷油、抗抑郁药、非吸收型抗菌药物等)以及心理行为干预。本文就IBS腹痛治疗现状和进展作一综述,以期为临床医师治疗IBS患者的腹痛提供依据。

Abdominal pain is a prominent syndrome in patients with irritable bowel syndrome(IBS),which greatly affects the quality of life of patients.Due to the complexity of etiology and great individual variation,abdominal pain treatment in IBS patients is still a clinical difficulty.The treatment of IBS pain includes non‑drug therapy(lifestyle intervention such as diet and exercise,gut microbiota modulation),drug therapy(antispasmodics,peppermint oil,antidepressants,non‑absorbed antibiotic)and psychological behavior intervention.This article reviewed the status and progress of pain treatment in IBS,so as to provide evidences for clinicians.