中医药对重症中暑患者血清炎症因子水平的影响

Effect of traditional Chinese medicine on serum inflammatory factors in patients with severe heatstroke

目的探讨安宫牛黄丸对重症中暑患者血清炎症因子水平的影响。方法选择2016年6月—2020年4月我院收治的60例重症中暑患者,根据随机平行分组法将其分为治疗组和对照组,每组各30例。对照组予以西医常规治疗,治疗组在对照组基础上加用安宫牛黄丸鼻饲治疗。对比两组治疗前后的血清炎症因子水平,观察治疗组的不良反应。结果两组治疗第7 d的炎症因子水平均较入院2 h降低,且治疗组均低于对照组,两组比较差异均有统计学意义(t=8.736、8.793、9.361,均P<0.05);治疗组在治疗过程中及治疗后未见明显不良反应。结论安宫牛黄丸可以降低重症中暑患者血清炎症因子水平,且用药安全。

ObjectiveTo evaluate the effect of Angong Niuhuang Pill on the level of serum inflammatory factors in severe heatstroke patients.Methods A total of 60 patients with severe heatstroke in our hospital from June 2016 to April 2020 were randomly divided into the control group and the treatment group,30 cases in each group.The patients in the control group were given conventional western medicine treatment,and in the treatment group were given Angong Niuhuang Pill nasogastric feeding on the basis of control group.The serum inflammatory factor levels before and after treatment were compared between the two groups,and the adverse effects of the treatment group were observed.Results The levels of inflammatory factors in both groups on the 7th day of treatment were lower than those in the 2 h of admission,and both treatment groups were lower than the control group,and the differences between the two groups were statistically significant(t=8.736,8.793,9.361,all P<0.05),no significant adverse reactions were seen in the treatment group during and after the treatment.Conclusion Angong Niuhuang Pill can reduce the serum levels of inflammatory factorin patients with severe heatstroke,and it is safe to use.