脑出血恢复期补阳还五汤加减联合康复治疗对患者生活质量及预后的影响

Effect of Combined Rehabilitation Therapy with Buyang Huanwu Decoction on Quality of Life and Prognosis of Patients with Cerebral Hemorrhage During Convalescence

目的:分析在脑出血恢复期采用补阳还五汤加减联合康复治疗的效果及对患者生活质量、预后效果的影响。方法:于本院抽选80例脑出血恢复期作为研究对象,以诊疗资料为研究主体参与2021年10月至2022年10月期间临床统计。对象按照入院时间先后顺序不同分出对照组(2021年10月至2022年3月)、试验组(2022年4月至2022年10月),每组40例患者均接受不同的治疗干预。对照组:康复治疗,试验组:康复治疗联合补阳还五汤加减治疗,比较脑血管功能、氧化应激指标、中医证候积分、神经功能缺损程度、运动功能、生活质量、治疗总有效率。结果:在治疗前对比脑血管功能,即脑血管平均流速及平均流量、血管动态阻力、血管外周阻力,无差异,P>0.05,治疗后,试验组脑血管平均流速及平均流量高于对照组,血管动态阻力、血管外周阻力低于对照组,P<0.05;治疗前,两组氧化应激指标,SOD、HO-1、GSH-PX水平相比无差异,P>0.05,治疗后,试验组SOD、HO-1、GSH-PX水平高于对照组,P<0.05;治疗前,对比中医证候积分,即心悸、头痛、眩晕、胸闷等评分,无差异,P>0.05,治疗后,以上症状评分2组均下降,而且试验组低于对照组,P<0.05;治疗前对比两组神经功能缺损程度、运动功能、生活质量,无差异,P>0.05,治疗后,神经功能缺损程度评分试验组低于对照组,而运动功能、生活质量评分试验组高于对照组,P<0.05;统计两组治疗效果,试验组治疗总有效率高于对照组,P<0.05。结论:在脑出血恢复期治疗中,开展补阳还五汤加减联合康复治疗方案,可以取得显著的效果,同时其对提高患者生活质量、预后效果有积极的影响,值得推荐。

Objective:To analyze the effect of combination of Buyang Huanwu decoction and reduction on the quality of life and prognosis of patients with cerebral hemorrhage during convalescence.Methods:Eighty convalescent patients with cerebral hemorrhage in Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine from October 2021 to October 2022 were selected as subjects.According to the order of admission time,40 patients admitted from October 2021 to March 2022 were divided into control group,and 40 patients admitted from April 2022 to October 2022 were divided into experimental group.The control group received conventional rehabilitation treatment,and the experimental group received conventional rehabilitation treatment combined with Buyang Huanwu decoction.Cerebrovascular function,oxidative stress index,TCM syndrome score,degree of neurological impairment,motor function,quality of life and total effective rate of treatment were compared between the two groups.Results:Before treatment,there was no statistically significant difference in cerebrovascular function(mean cerebrovascular velocity and flow,dynamic vascular resistance,peripheral vascular resistance)between the two groups(P>0.05).After treatment,the mean cerebrovascular velocity and flow of the experimental group were higher than that of the control group,while the dynamic vascular resistance and peripheral vascular resistance were lower than that of the control group.The differences were statistically significant(P<0.05).Before treatment,the oxidative stress indexes,SOD,HO-1 and GSH-PX levels of the two groups had no statistical significance(P>0.05).After treatment,SOD,HO-1 and GSH-PX levels of the experimental group were higher than those of the control group,with statistical significance(P<0.05).Before treatment,there was no significant difference in TCM syndrome scores(palpitation,headache,vertigo,chest tightness,etc.)between the two groups(P>0.05).After treatment,TCM syndrome scores(palpitation,headache,vertigo,chest tightness,etc.)decreased in both groups,and the test group was lower than the control group,the difference was statistically significant(P<0.05).Before treatment,there were no statistically significant differences in the degree of neurological impairment,motor function and quality of life between the two groups(P>0.05).After treatment,the score of neurological impairment in the experimental group was lower than that in the control group,while the score of motor function and quality of life in the experimental group was higher than that in the control group,with statistical significance(P<0.05).The total effective rate of experimental group was higher than that of control group,and the difference was statistically significant(P<0.05).Conclusion:In the convalescent treatment of cerebral hemorrhage,the combination of Buyang Huanwu decoction and reduction can achieve significant results,and it has a positive impact on improving the quality of life and prognosis of patients.