外周血相关指标对急性非静脉曲张性上消化道出血治疗需求的预测效能

The effectiveness of peripheral blood indexes in predicting therapeutic schemes of acute non-variceal upper gastrointestinal bleeding patients

目的 探讨红细胞分布宽度(RDW)、血小板分布宽度(PDW)、平均血小板体积(MPV)预测急性非静脉曲张性上消化道出血(ANVUGIB)患者对输血或内镜/手术治疗需求的效能.方法 选取广州医科大学附属第四医院急诊收治的ANVUGIB患者106例,根据是否给予输血或内镜/手术治疗,分为一般治疗组和特殊治疗组.比较两组一般资料及RDW、PDW、MPV水平,采用受试者工作特征曲线分析RDW、PDW、MPV预测ANVUGIB患者治疗方案的效能.结果 一般治疗组73例患者,特殊治疗组33例患者.特殊治疗组的收缩压、血红蛋白、血小板计数低于一般治疗组(P<0.05),RDW、PDW、MPV水平高于一般治疗组(P<0.001).RDW、PDW、MPV预测需要特殊治疗的ROC曲线下面积分别为0.951、0.726、0.856.结论 RDW、PDW、MPV对ANVUGIB患者治疗方案的选择具有预测价值,为采取及时有效的个体化治疗提供依据.

Objective To investigate the effectiveness of RDW,PDW,MPV in the prediction of need for blood transfusion or endoscopic/surgical treatment in ANVUGIB patients.Methods 106 ANVUGIB patients of emergency department were selected.According to whether they received blood transfusion or endoscopic/surgical treatment,they were divided into general treatment group and special treatment group.The general data,RDW,PDW and MPV levels in the two groups were compared.Receiver operating characteristic curve(ROC)was used to analyze the effectiveness of RDW,PDW,MPV in predicting therapeutic schemes.Results ANVUGIB patients were divided into general treatment group(n=73)and special treatment group(n=33).The systolic pressure,hemoglobin and platelet count of special treatment group were lower than those of general treatment group(P<0.05),while the level of RDW,PDW and MPV were higher than those of the general treatment group(P<0.001).The area under curve of RDW,PDW and MPV in predicting therapeutic schemes was 0.951,0.726,0.856,respectively.Conclusions The detection of whole blood RDW,PDW and MPV has predictive value for the therapeutic schemes of ANVUGIB patients,providing a basis for timely and effective treatment.