体外膜肺氧合在成人脓毒症患者救治中的发展及临床应用

Development and clinical application of extracorporeal membrane oxygenation in the treatment of adult sepsis patients

体外膜肺氧合(extracorporeal membrane oxygenation,ECMO)简称膜肺,是目前救治垂危患者生命的新技术。脓毒症相关死亡仍是世界范围内的重大难题,尽管近10年在脓毒症患者的救治上取得很多新进展,其病死率依旧很高。成人脓毒症治疗机制复杂,脓毒症导致的严重急性呼吸窘迫综合征并不罕见,通常需要使用ECMO技术进行支持性辅助治疗。然而,ECMO在脓毒症患者中的临床应用还存在争议。本文就ECMO技术在成人脓毒症治疗中的应用作一综述。

Extracorporeal membrane oxygenation(ECMO)is a new technology currently available to save the lives of critically ill patients.Sepsis-related deaths remain a major problem worldwide,and despite many new advances in the treatment of septic patients in the last decade,the morbidity and mortality rates remain high.The treatment mechanism of sepsis in adults is complex,and severe acute respiratory distress syndrome due to sepsis is not uncommon and usually requires supportive adjunctive therapy using ECMO techniques.However,the clinical application of ECMO in sepsis patients is controversial.This article reviews the application of ECMO techniques in the treatment of sepsis in adults.