复方苦参注射液辅助EC-T方案治疗乳腺癌改良根治术后患者临床观察

Efficacy observation of compound Kushen injection and EC-T regimen on patients after modified radical mastectomy

目的:观察复方苦参注射液辅助EC-T方案治疗乳腺癌改良根治术后患者的临床疗效。方法:选取符合纳入标准的94例乳腺癌术后患者,随机分为两组各47例。对照组术后予EC-T方案进行化疗,治疗组在对照组基础上予复方苦参注射液治疗。观察两组临床疗效。结果:治疗组总有效率89.36%明显高于对照组的68.09%(P﹤0.05)。治疗后,两组患者的肿瘤标志物含量均较治疗前下降(P﹤0.05),且治疗组较对照组下降明显(P﹤0.05);两组患者免疫功能相关指标整体水平较均治疗前上升(P﹤0.05),且治疗组较对照组上升趋势更明显(P﹤0.05);治疗组WBC、HGB、PLT水平较对照组改善明显(P﹤0.05)。结论:复方苦参注射液辅助EC-T方案治疗乳腺癌改良根治术后患者,能增强疗效,降低不良反应发生率。

Objective:To observe the clinical efficacy of compound Kushen injection and EC-T regimen on patients after modified radical mastectomy.Methods:94 cases of eligible patients after modified radical mastectomy were randomly divided into two groups,47 cases in each group.The control group was treated with EC-T regimen for chemotherapy after operation,while the treatment group was treated plus with compound Kushen injection on the basis of control group.The clinical efficacy was observe in two groups.Results:The total effective rate of treatment group was 89.36%,which was significantly higher than 68.09%of control group(P﹤0.05).After treatment in both groups,the content of tumor markers of patients was decreased compared with before treatment(P﹤0.05),and the decrease of treatment group was more significant than that of control group(P﹤0.05).The overall level of indexes related to immune function of patients was increased in both groups compared with before treatment(P﹤0.05),and the increasing trend of treatment group was more obvious than that of control group(P﹤0.05).The levels of WBC,HGB and PLT of treatment group were significantly improved compared with those of control group(P﹤0.05).Conclusion:Compound Kushen injection and EC-T regimen for treating patients after modified radical mastectomy can enhance the clinical efficacy and reduce the incidence of adverse reactions.