阿立哌唑联合无抽搐电休克疗法治疗精神分裂症的效果

Effect of aripiprazole combined with non-convulsive electroconvulsive therapy in the treatment of schizophrenia

目的探究在精神分裂症治疗中,采用阿立哌唑联合无抽搐电休克疗法(MECT)的疗效,同时研究其对患者糖脂代谢,甲状腺功能及血清神经营养因子水平的影响。方法选取本院精神分裂症患者86例作为研究对象,收治时间为2021年10月-2022年10月,随机分组,常规组43例,采用无抽搐电休克疗法进行治疗,实验组43例,采用阿立哌唑联合无抽搐电休克疗法进行治疗,对比两组患者的治疗效果。结果实验组患者治疗后,治疗效果,脂代谢,甲状腺功能,血清神经营养因子水平等相关指标明显好于常规组,差异明显(P<0.05)。结论在精神分裂症患者治疗中,采用阿立哌唑联合无抽搐电休克疗法,可有效提升患者的治疗效率,对患者糖脂代谢,甲状腺功能及血清神经营养因子水平改善也具有重要影响,值得推广。

Objective To explore the fficacy of Aripiprazole combined with modifed electroconvulsive therapy(MECT)in the treatment of schizophrenia,and to study its effects on glucose and lipid metabolism,thyroid function and serum Neurotrophin levels.Methods 86 schizophrenic patients in our hospital were selected as the research object.The patients were randomly divided into the conventional group(43 cases)and the experimental group(43 cases).The experimental group(43 cases)were treated with Aripiprazole combined with non convulsive electroconvulsive therapy,and the therapeutic efts of the two groups were compared.Results After treatment,the treatment effect,lipid metabolism,thyroid function,serum Neurotrophin level and other related indicators in the experimental group were signifcantly better than those in the conventional group(P<0.05).Conclusion the treatment of schizophrenie patients,Aripiprazole combined with non convulsive electroconvulsive therapy can ffectively improve the treatment fficiency of patients,and has an important impact on the improvement of glucose and lipid metabolism,thyroid function and serum Neurotrophin levels of patients,which is worth promoting.