阿尔茨海默病患者病感缺失的研究进展

Research progress on anosognosia in Alzheimer's disease patients

阿尔茨海默病以记忆功能障碍、失语、失用、失认、视觉与空间技能受损、行动功能障碍以及性格与行为变化等全面性的痴呆症状为特点,但患者并不总是能意识到这种损害。本文就近年来阿尔茨海默病患者的病感缺失表现的概念、临床特征、诊断方法、病理生理、影像表现的相关研究进展进行综述,以提高对阿尔茨海默病患者中病感缺失症状的了解和认识。

Alzheimer's disease is characterized by comprehensive dementia symptoms such as memory dysfunction,aphasia,apraxia,agnosia,impaired visual and spatial skills,motor dysfunction,and personality and behavioral changes,but patients are not always aware of this impairment.This article reviews the concept,clinical features,diagnostic methods,pathophysiology and imaging manifestations of anosognosia in Alzheimer's disease patients in recent years,so as to improve the understanding and knowledge of the symptoms of anosognosia in Alzheimer's patients.