无创呼吸机治疗COPD急性加重合并Ⅱ型呼衰的临床效果观察

Clinical Effect of Noninvasive Ventilator in the Treatment of Acute Exacerbation of COPD Complicated with Type II Respiratory Failure

目的:探讨无创呼吸机治疗COPD急性加重合并Ⅱ型呼衰的临床效果。方法:选取2020年4月~2021年9月收治的80例COPD急性加重合并Ⅱ型呼衰患者作为研究对象,采用随机数字表法将其分为对照组和观察组,各40例,对照组接受常规治疗,观察组接受常规治疗+无创呼吸机治疗,比较两组患者治疗疗效、症状消失时间、血气指标等。结果:观察组治疗疗效95%高于对照组的75%,差异有统计学意义(χ^(2)=6.2745,P<0.05);观察组喘憋消失时间、肺部啰音消失时间、住院时间短于对照组,差异有统计学意义(t=45.5217,44.4345,41.9877,P<0.05);两组患者治疗前Pa CO_(2)、Pa O_(2)、Sa O_(2)比较无统计学意义(P>0.05),治疗后,观察组Pa CO_(2)低于对照组,Pa O_(2)、Sa O_(2)高于对照组,差异有统计学意义(t=7.8831,25.3259,12.1858,P<0.05)。结论:COPD急性加重合并Ⅱ型呼衰患者在常规治疗基础上,再给予无创呼吸机辅助治疗,能促进症状消失,更好地改善血气指标,进而提升疗效。

Objective:To explore the clinical effect of noninvasive ventilator in the treatment of acute exacerbation of COPD complicated with type II respiratory failure.Methods:80 patients with acute exacerbation of COPD complicated with type II respiratory failure treated from April 2020 to September 2021 were selected as the research object.They were randomly divided into control group and observation group,with 40 cases in each group.The control group received routine treatment and the observation group received routine treatment+noninvasive ventilator treatment.The therapeutic efficacy,symptom disappearance time and blood gas indexes of the two groups were compared.Results:The therapeutic effect of the observation group was 95%higher than that of the control group 75%,the difference was statistically significant(χ^(2)=6.2745,P<0.05);The observation group showed a statistically significant difference in the disappearance time of wheezing,lung rales,and hospital stay compared to the control group(t=45.5217,44.4345,41.9877,P<0.05);Before treatment,PaCO_(2),PaO_(2) and SaO_(2) were compared between the two groups(P>0.05).After treatment,PaCO_(2) in the observation group was lower than that in the control group,PaO_(2) and SaO_(2) were higher than those in the control group(t=7.8831,25.3259,12.1858,P<0.05).Conclusion:On the basis of routine treatment,patients with acute exacerbation of COPD combined with type II respiratory failure can be treated with noninvasive ventilator,which can promote the disappearance of symptoms,better improve blood gas indexes,and then improve the curative effect.