丘脑混合性生殖细胞瘤一例并文献复习

Thalamic Mixed Germ Cell Tumor:A Case Report and Literature Review

本文报道丘脑混合性生殖细胞瘤1例。患者男,15岁,因头痛2周、神智不清2天入院。MRI表现为左侧丘脑占位累及中脑,肿块成分异常复杂,包含稍长T1稍长T2信号伴明显强化区域、多发小囊性无强化区、短T1短T2信号出血区、周围环绕分隔的无强化短T1长T2信号区,肿块周围伴明显水肿带,肿块压迫第三脑室及中脑导水管导致幕上脑积水。最终病理诊断为丘脑混合性生殖细胞瘤(包含生殖细胞瘤、卵黄囊瘤和恶性畸胎瘤3种成分)。

A case of thalamic mixed germ cell tumor is reported.A 15-year-old male patient was admitted to the hospital due to headache for two weeks and unconsciousness for two days.MRI showed that the space occupying lesion of the left thalamus involved the midbrain,and the mass composition was unusually complex,including slightly long T1 and slightly long T2 signal with obvious enhancement area,multiple small cystic non enhancement area,short T1 and short T2 signal hemorrhage area,non-enhanced short T1 and long T2 signal area surrounded by the partition,obvious edema zone around the mass,and the mass compressed the third ventricle and midbrain aqueduct,leading to supratentorial hydrocephalus.The final pathological diagnosis was thalamic mixed germ cell tumor(including germ cell tumor,yolk sac tumor and malignant teratoma).