基于COMSOL的乳腺癌光声检测仿真研究

Simulation Study of Photoacoustic Detection of Breast Cancer Based on COMSOL

在COMSOL Multiphysics中建立光声检测的有限元模型,模拟在激光脉冲作用下乳腺组织中光—热—声转换的过程以及该过程中光能量、温度、位移和声压数值的变化。结果表明,乳腺组织在接受脉冲激光辐照时,组织内部肿瘤处的光能量值大约是其周围正常组织的81%,温度与正常组织相比略高,最高约为0.28 K,由瞬态热膨胀产生的超声压力波最高约为5 kPa,中心频率为10 MHz。进而说明所建立的光声转换过程切实有效,有助于区分正常组织和病变肿瘤组织,实现乳腺癌的早期诊断与治疗。

Establish a finite element model for photoacoustic detection in COMSOL Multiphysics to simulate the process of light-heat-sound conversion in breast tissue under the action of laser pulses,as well as the changes in light energy,temperature,displacement,and sound pressure values during this process.The results show that when breast tissue is irradiated by pulsed laser,the light energy value at the tumor site inside the tissue is about 81%of that of the surrounding normal tissue.The temperature is slightly higher than that of normal tissue,with a maximum of about 0.28 K.The ultrasonic pressure wave generated by transient thermal expansion is about 5 kPa,with a central frequency of 10 MHz.This further shows that the established photoacoustic conversion process is effective and helpful to distinguish between normal tissue and diseased tumor tissue,achieving early diagnosis and treatment of breast cancer.