针刺结合康复技术及疏血通注射液对高血压脑出血小骨窗开颅血肿清除术后患者神经功能的影响

Effect of acupuncture combined with rehabilitation technique and Shuxuetong injection on neurological function in patients with hypertensive intracerebral hemorrhage after small bone window craniotomy hematoma removal

目的探讨针刺结合康复技术及疏血通注射液对高血压脑出血(HICH)小骨窗开颅血肿清除术后患者神经功能的影响。方法选取2021年1月至2022年10月于酒泉市人民医院接受小骨窗开颅血肿清除术治疗的84例HICH患者作为研究对象,按治疗方法将其分为对照组和观察组,每组42例。对照组从术后1周开始给予乙酰谷酰胺与鼠神经生长因子治疗,观察组从术后1周开始给予针刺结合康复技术及疏血通注射液治疗。比较两组的治疗效果。结果治疗后,两组的Fugl-Meyer运动量表(FMA)评分较治疗前升高,中国脑卒中临床神经功能缺损程度评分量表(CSS)评分较治疗前降低,且观察组优于对照组(P<0.05)。治疗后,两组的转化生长因子β_(1)(TGF-β_(1))、血管内皮生长因子(VEGF)及环磷酸腺苷(c AMP)水平较治疗前升高,环磷酸鸟苷(c GMP)水平较治疗前降低,且观察组优于对照组(P<0.05)。观察组的治疗总有效率为95.24%,显著高于对照组的78.57%(P<0.05)。结论针刺结合康复技术及疏血通注射液治疗HICH小骨窗开颅血肿清除术后患者具有显著效果,可改善其运动功能及神经功能,增强神经与血管的再生能力,进而提高康复效果,值得临床推广及应用。

Objective To explore the effect of acupuncture combined with rehabilitation technique and Shuxuetong injection on neurological function in patients with hypertensive intracerebral hemorrhage(HICH)after small bone window craniotomy hematoma removal.Methods A total of 84 patients with HICH who underwent small bone window craniotomy hematoma removal in the Jiuquan City People's Hospital from January 2021 to October 2022 were selected as the research objects,and the patients were divided into control group and observation group according to the treatment methods,with 42 cases in each group.The control group was treated with aceglutamide and mouse nerve growth factor starting from 1 week after operation,and the observation group was treated with acupuncture combined with rehabilitation technique and Shuxuetong injection starting from 1 week after operation.The therapeutic effects of the two groups were compared.Results After treatment,the score of Fugl-Meyer Assessmen(FMA)in the two groups was higher than that before treatment,the score of China Stroke Scale(CSS)in the two groups was lower than that before treatment,and thoses in the observation group were better than the control group(P<0.05).After treatment,the levels of transforming growth factor-β_(1)(TGF-β_(1)),vascular endothelial growth factor(VEGF)and cyclic adenosine monophosphate(cAMP)in the two groups were higher than those before treatment,the level of cyclic guanosine monophosphate(cGMP)was lower than that before treatment,and those in the observation group were better than the control group(P<0.05).The total effective rate of treatment in the observation group was 95.24%,which was significantly higher than 78.57%in the control group(P<0.05).Conclusion Acupuncture combined with rehabilitation technique and Shuxuetong injection in the treatment of HICH patients after small bone window craniotomy hematoma removal has a significant effect. It can improve their motor function and neurological function, enhance the regeneration ability of nerves and blood vessels, and then improve their rehabilitation effect. It is worthy of clinical promotion and application.