子宫内膜异位症的发病机制与临床诊疗研究进展

Research advances on pathogenesis and clinical diagnosis and treatment of endometriosis

子宫内膜异位症是一种与不孕症相关的常见病症,它会导致女性出现慢性疼痛,严重影响女性的身体健康及生活质量。子宫内膜异位症是指子宫腔被覆内膜及子宫以外的部位存在具有活性的子宫内膜细胞。目前,临床上子宫内膜异位症的诊断尚缺乏有效的非侵入性生物标志物,并且临床上子宫内膜异位症仍然不能根治,且复发率高。近年来,相关研究表明,尽管子宫内膜异位症的病因仍不确定,但血管生成、激素和免疫因素都与导致症状发展的机制具有一定相关性。该文就子宫内膜异位症相关发病机制和临床诊断与治疗研究进展进行综述,旨在为该疾病的诊疗提供科学依据。

Endometriosis is a common disease associated with infertility,which can cause chronic pain in women and seriously affect their health and quality of life.Endometriosis refers to the presence of active endometrial cells in the lining of the uterine cavity and outside the uterus.At present,there is still a lack of effective non-invasive biomarkers for the diagnosis of endometriosis,and endometriosis still cannot be fundamentally cured,and the recurrence rate is high.In recent years,relevant studies have shown that although the etiology of endometriosis is still uncertain.However,angiogenesis,hormonal and immune factors are all related to the mechanisms of the symptoms development.This article reviews the research progress in the pathogenesis,clinical diagnosis and treatment of endometriosis,aiming to provide scientific basis for the diagnosis and therapy of this disease.