中医综合外治疗法联合rTMS对原发性失眠的疗效评价

Evaluation of comprehensive external therapy of traditional Chinese medicine combined with rTMS in primary insomnia

目的:探索中医综合外治疗法联合重复经颅磁刺激(Repetitive transcranial magnetic stimulation, rTMS)治疗原发性失眠的临床效果。方法:选取原发性失眠患者120例为研究对象,随机分为治疗组和对照组,治疗组给予失眠心理行为和rTMS治疗7天,7天后加用中医综合外治疗法,共治疗2周;对照组给予失眠心理行为治疗及单纯rTMS治疗,共治疗2周。比较两组患者治疗疗效、匹兹堡睡眠指数(Pittsburgh Sleep Quality Index, PSQI)评分、抑郁自评量表(Self-rating Depression Scale, SDS)评分及焦虑自评量表(Self-rating Anxiety Scale, SAS)评分。结果:在PSQI、SAS和SDS评分上,两组治疗后均低于治疗前(P<0.05),且治疗组低于同期对照组(P<0.05);治疗组总有效率高于对照组(P<0.05)。结论:中医综合外治疗法联合rTMS治疗原发性失眠患者疗效优于单纯rTMS疗效。

Objective:To explore the clinical effect of traditional Chinese medicine combined with repetitive transcranial magnetic stimulation(rTMS)in the treatment of primary insomnia.Methods:A total of 120 cases with primary insomnia were randomly divided into treatment group and control group.The treatment group was given insomnia psychobehavioral therapy and rTMS for 7 days,and on this basis,this group was treated further with comprehensive external therapy of traditional Chinese medicine for another 7 days,(for a total of 14 days).The control group was given psychobehavioral therapy for insomnia and rTMS alone for a total of 14 days.The curative effect,Pittsburgh Sleep Quality Index(PSQI),Self-rating Depression Scale(SDS)and Self-rating Anxiety Scale(SAS)of the two groups were compared,and the results were statistically analyzed.Results:The scores of PSQI,SAS and SDS in the treatment group and the control group were lower than those before treatment(P<0.05),and the scores in the treatment group were lower than those in the control group in the same period(P<0.05);The total effective rate of the treatment group was higher than that of the control group(P<0.05).Conclusion:The efficacy of comprehensive external therapy of traditional Chinese medicine combined with rTMS was superior to that of rTMS only in patients with primary insomnia.