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细菌性脑膜炎患儿发生药源性迟发型皮肤超敏反应1例分析

Analysis of A Case of Drug-induced Delayed Skin Hypersensitivity in Children with Bacterial Meningitis
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摘要 目的为临床药师参与细菌性脑膜炎患儿发生药源性迟发型皮肤超敏反应药学监护提供参考。方法因合并用药种类较多,细菌性脑膜炎1例在治疗过程中出现迟发型药疹,临床药师经过药物治疗分析和评价,为临床医生提供相应的调整策略,优化治疗方案并提供全程化药学监护。结果此例患儿感染等症状控制,治愈出院。结论临床药师能在细菌性脑膜炎患者治疗的过程中协助临床医师不断优化调整方案,为患者的治疗起到积极的作用。 Objective To provide reference for clinical pharmacists to participate in pharmaceutical care of drug-induced delayed skin hypersensitivity in children with bacterial meningitis.Methods Due to a variety of drug combinations,delayed drug eruption occurred in 1 case of bacterial meningitis in the course of treatment.Clinical pharmacists provided corresponding adjustment strategies,optimized treatment plans and whole-process pharmaceutical care for clinicians after analysis and evaluation of drug therapy.Results Eventually,the child's infection and other symptoms were controlled,cured and discharged.Conclusion Clinical pharmacists can help clinicians optimize and adjust the program during the treatment of patients with bacterial meningitis,and play a positive role in the treatment of patients.
作者 彭妍 钟斌 陈芳辉 PENG Yan;ZHONG Bin;CHEN Fanghui(The First Affiliated Hospital of Gannan Medical University,Ganzhou Jiangxi 341000,China)
出处 《药品评价》 CAS 2023年第5期595-598,共4页 Drug Evaluation
关键词 细菌性脑膜炎 超敏反应 迟发型 头孢曲松 药物相关性副作用和不良反应 临床药师 药学监护 Bacterial meningitis Hypersensitivity,delayed Ceftriaxone Drug-related side effects and adverse reactions Clinical pharmacist Pharmaceutical care
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  • 1杜文民,王永铭,程能能.药物不良反应的判定与其研究方法(续一)[J].中国药物警戒,2004,1(2):17-20. 被引量:16
  • 2钟松阳,张慧光.87例头孢曲松钠所致不良反应综合分析[J].中国医院药学杂志,2006,26(11):1447-1448. 被引量:16
  • 3黄宇虹,张伯礼.单一事件药物不良反应的因果关系评价[J].中国临床药理学与治疗学,2007,12(6):697-699. 被引量:4
  • 4Roychowdhury S, Svensson CK. Mechanisms of drug-induced delayed-type hypersensitivity reactions in the skin. AAPS J, 2005, 7(4): E834-846.
  • 5Pichler WJ. Delayed drug hypersensitivity reactions. Ann Intern Med, 2003, 139(8): 683-689.
  • 6Porebski G, Gschwend-Zawodniak A, Pichler WJ. In vitro diagnosis of T cell-mediated drug allergy. Clin Exp Allergy, 2011, 41(4): 461-470.
  • 7Posadas SJ, Pichler WJ. Delayed drug hypersensitivity reactions -new concepts. Clin Exp Allergy, 2007, 37(7): 989-999.
  • 8Shiohara T, Mizukawa Y, Teraki Y. Pathophysiology of fixed drug eruption: the role of skin-resident T cells. Curr Opin Allergy Clin Immunol, 2002, 2(4): 317-323.
  • 9Schaerli P, Ebert L, Willimann K, et al. A skin-selective homing mechanism for human immune surveillance T cells. J Exp Med, 2004, 199(9): 1265-1275.
  • 10Lissia M, Mulas P, Bulla A, et al. Toxic epidermal necrolysis (Lyell's disease). Burns, 2010, 36(2): 152-163.

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