间质性膀胱炎/膀胱疼痛综合征诊治进展

Latest advances in the diagnosis and treatment of interstitial cystitis/bladder pain syndrome

间质性膀胱炎/膀胱疼痛综合征(IC/BPS)是表现为与膀胱相关的疼痛、压迫感或不适且伴有下尿路症状,症状持续6周(或6个月)以上的一组症候群。自首次报道至今,该病始终是临床诊治的难题,也一直经历着认知革新,其涉及疾病分类分型、相关基础研究、影像学、症状评分、膀胱镜检、治疗以及新的潜在治疗靶点内源性大麻素系统等诸多方面,亦是本文要点。

Interstitial cystitis/bladder pain syndrome(IC/BPS)is characterized by pain,oppressing sensation,or discomfort associated with the bladder,accompanied by lower urinary tract symptoms,lasting for more than 6 weeks(or 6 months).Since IC/BPS was first reported,its diagnosis and treatment have been a challenge to clinicians.This article will review its classification and phenotype,fundamental research,imaging,symptom score,cystoscopy,treatment and potential therapeutic targets.