1例危险罗尔斯顿菌致中枢神经系统感染治疗的药学监护

Pharmaceutical care for a case of central nervous system infection caused by Ralstonia insidiosa

目的对1例危险罗尔斯顿菌致中枢神经系统感染患者的治疗进行药学监护,为临床用药提供参考。方法临床药师通过参与1例腰椎骨折术后危险罗尔斯顿菌致中枢神经系统感染患者的治疗,同医生一起为患者制定个体化抗感染方案,协助医生做好抗菌药物品种选择、用法用量的设定、治疗期间抗感染效果评估和不良反应监测。结果通过临床药师的协助,抗感染药物的经验性选择更加规范,对目标细菌的抗感染治疗更加精准,患者经注射用头孢吡肟联合左氧氟沙星注射液抗感染治疗,临床症状基本消失,各项感染指标恢复正常,未发生药物不良反应。结论临床药师参与治疗并进行药学监护,有利于提升临床用药的规范性和合理性,保障用药安全。

Objective To provide pharmaceutical care for a patient with central nervous system infection caused by Ralstonia insidiosa,and to provide reference for clinical drug use.Methods Clinical pharmacists participated in the treatment of a patient with central nervous system infection caused by Ralstonia insidiosa after lumbar fracture surgery,worked with clinicians to develop individualized anti-infective program for the patient,and assisted doctors in the selection of antibacterial drugs,the setting of usage and dosage,the evaluation of anti-infective effect and the monitoring of adverse reactions during treatment.Results With the assistance of clinical pharmacists,the empirical selection of anti-infective drugs was more standardized,and the anti-infective treatment of target bacteria was more accurate.After the anti-infective treatment with cefepime for injection combined with levofloxacin injection,the clinical symptoms basically disappeared,all infection indexes returned to normal,and no adverse drug reactions occurred.Conclusion Participation of clinical pharmacists in the treatment and pharmaceutical care is beneficial to improve the standardization and rationality of clinical drug use to ensure the safety of drug use.