摘要
二甲双胍是2型糖尿病的一线治疗药物,目前也逐渐用于皮肤病的治疗,包括银屑病等。本文综述二甲双胍治疗银屑病的机制及临床研究进展,为皮肤科治疗银屑病尤其是银屑病合并代谢性疾病提供思路和方法。
Metformin,the first-line treatment of type 2 diabetes,has been also increasingly used in the treatment of some skin diseases,such as psoriasis.This review summarizes therapeutic mechanisms of and clinical research progress in metformin in the treatment of psoriasis,aiming to provide ideas and methods for the treatment of psoriasis,especially psoriasis complicated by metabolic diseases.
作者
陈小敏
张景展
丁媛
康晓静
Chen Xiaomin;Zhang Jingzhan;Ding Yuan;Kang Xiaojing(Department of Dermatology and Venereology,People′s Hospital of Xinjiang Uygur Autonomous Region,Urumqi 830001,China)
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2023年第8期799-802,共4页
Chinese Journal of Dermatology
基金
新疆维吾尔自治区人民医院院级课题(20190106)。
关键词
银屑病
二甲双胍
治疗
NF-κB
MTOR
ERK1/2
STAT
NLRP3
Psoriasis
Metformin
Therapy
NF-kappa B
Mechanistic target of rapamycin
Extracellular signal-regulated kinase
Signal transducing activator of transcription
Nucleotide-binding oligomerization domain-like receptor protein 3
