丙泊酚相关尿液颜色变化及其机制

Propofol related urine discoloration and its mechanism

丙泊酚广泛用于患者围手术期麻醉诱导和维持及ICU患者的镇静等,丙泊酚输注引起的尿液颜色变化是一种良性过程,无肾毒性,停止输注后,患者尿液颜色一般均可恢复正常。文章综述了丙泊酚输注引起的粉红尿、绿色尿和白色尿的临床特点,总结了尿液颜色变化的相关机制。未来仍需进一步观察丙泊酚所致尿液颜色变化对患者的长期影响并深入探索其发生机制,以期为临床工作者提供诊治思路。

Propofol is widely used in anesthesia induction and maintenance,and sedation in intensive care unit.Propofol in‑duced urine discoloration is a benign change,without nephrotoxicity,and the color of urine can usually return to normal once propofol infusion is discontinued.The article reviews the clinical characteristics of pink,green,and white urine after propofol infusion and sum‑marizes the related mechanisms of urine discoloration involved.Further research is needed to evaluate the long term outcome of propo‑fol related urine discoloration and to explore its related mechanisms,in order to provide thoughts for the diagnosis and treatment for medical staff.