SOFA评分在评估重症监护室多器官功能衰竭发生率中的应用

Application of SOFA Score in Assessing the Incidence of Multiple Organ Failure in Intensive Care Unit

目的探讨序贯器官衰竭(SOFA)评分在评估重症监护室多器官功能衰竭发生率中的应用效果。方法选取2021年1月-2023年1月新疆维吾尔自治区中医医院收治的发生多器官功能衰竭的50例患者作为研究对象,将其设为观察组,另选取同期在新疆维吾尔自治区中医医院治疗的50例患者设为对照组,对比两组患者SOFA评分,并分析SOFA评分对多器官功能衰竭的诊断效能。对观察组患者进行院内随访,将院内28 d死亡的21例患者设为死亡组,将其余29例存活的患者设为存活组,对比两组患者临床一般情况,并分析SOFA评分对于多器官功能衰竭的预后预测价值。结果对照组患者SOFA评分低于观察组(P<0.05)。通过绘制ROC曲线,结果显示,SOFA评分诊断多器官功能衰竭曲线下面积为0.832,特异度为91.47%,敏感度为73.59%,临床综合诊断的曲线下面积为0.891,特异度为98.52%,敏感度为90.26%;存活组与死亡组患者性别、身体质量指数(BMI)、合并基础疾病、入住ICU时间比较,差异无统计学意义(P>0.05),存活组与死亡组患者年龄、APACHEⅡ评分、SOFA评分比较,差异有统计学意义(P<0.05);通过Logistic回归分析,SOFA评分为多器官功能衰竭患者预后情况的独立预测指标(P<0.05)。结论SOFA评分能够有效评估多器官功能衰竭的发生情况,且敏感度和特异度均比较高,同时SOFA评分也能够辅助预测多器官功能衰竭的预后情况。临床上针对SOFA评分较高的患者需及时改良治疗方案,预防患者预后不良情况发生。

Objective To explore the application effect of sequential organ failure(SOFA)score in assessing the incidence of multiple organ failure in intensive care unit.Methods A total of 50 patients with multiple organ failure admitted to the intensive care unit of our hospital from January 2021 to January 2023 were selected as the study subjects,and divided into the observation group,and 50 patients who were treated in the intensive care unit at the same time were selected as the control group.The SOFA scores of the two groups were compared,and the diagnostic effi cacy of SOFA scores on multiple organ failure was analyzed.All patients were followed up in the hospital,21 patients who died 28 days in the hospital were divided into death group,and the remaining 29 patients were divided into survival group.The general clinical conditions of the two groups were compared,and the prognostic value of SOFA score for multiple organ failure in intensive care unit was analyzed.Results The SOFA score of patients in the control group was lower than that in the observation group(P<0.05).By drawing the ROC curve,the results showed that the area under the curve of SOFA score diagnosis of multiple organ failure was 0.832,the specifi city was 91.47%,the sensitivity was 73.59%,and the area under the curve of clinical comprehensive diagnosis was 0.891,the specifi city was 98.52%,the sensitivity was 90.26%.There was no signifi cant diff erence between the survival group and the death group in terms of sex,BMI,basic disease,and time of admission to ICU(P>0.05),but there was signifi cant diff erence between the survival group and the death group in terms of age,APACHE II score,and SOFA score(P<0.05).The results of logistic regression analysis showed that SOFA score was an independent predictor of multiple organ failure(P<0.05).Conclusion SOFA score can effectively evaluate the occurrence of multiple organ failure in intensive care unit with high sensitivity and specifi city.Meanwhile,SOFA score can also help predict the prognosis of multiple organ failure in intensive care unit.Clinically,patients with high SOFA scores need to improve the treatment plan in time to prevent the occurrence of poor prognosis.