真菌球型鼻窦炎鼻内镜术后不同致病菌种类预后的临床观察

Clinical observation on prognosis of pathogenic bacteria species after endoscopic operation of fungal globular rhinosinusitis

目的通过对功能性鼻内镜手术的真菌球型鼻—鼻窦炎患者的临床资料分析,得出不同菌群对患者术后上皮化时间的影响,为真菌球型鼻—鼻窦炎的诊疗提供帮助。方法选取在全麻下行FESS治疗,且术后病理检查确诊为曲霉菌或毛霉菌的真菌球型鼻—鼻窦炎患者120例作为研究对象。按照是否伴有鼻息肉和鼻中隔偏分为4组:A组单纯患病组,B组鼻中隔偏曲组,C组鼻息肉组,D组鼻中隔偏曲及鼻息肉组;各组互为对照组,研究各患病组之间真菌菌群的分布差异。以SNOT-20量表对各组患者术腔黏膜上皮化的时间做分析,研究不同真菌和各患病组类型对术后上皮化的影响。结果曲霉菌和毛霉菌在各患病组中的分布无明显差异(P>0.05)。真菌种类对术后上皮化时间的影响无差异(P>0.05)。结论致病真菌种类与是否伴发鼻息肉和(或)鼻中隔偏曲无相关性。真菌种类对术腔术后上皮化无影响。

Objective To analyze the clinical data of patients with fungal bulbous rhinosinusitis through functional endoscopic sinus surgery,find out the influence of different flora on postoperative epithelialization time of patients,so as to provide help for the diagnosis and treatment of fungal bulbous rhinosinusitis.Methods 120 patients with fungal globular rhinosinusitis diagnosed as aspergillus or mucor by postoperative pathological examination by postoperative pathological examination after FESS treatment under general anesthesia were selected as the study subjects.They were divided into 4 groups according to whether there were nasal polyps and nasal septum deviation.A group was simple disease group,B group was nasal septum deviation group,C group was nasal polyp group,D group was nasal septum deviation and nasal polyp group.Each group was the control group,and studied the distribution difference of fungal microflora among each group.Snot-20 scale was used to analyze the time of intraoperative mucosal epithelialization in each group and study the influence of different fungi and types of each disease group on postoperative epithelialization.Results Aspergillus and mucor showed that there no significant difference in distribution in each disease group(P>0.05).There was no difference in the influence of fungus species on postoperative epithelialization time(P>0.05).Conclusions There is no correlation between the type of pathogenic fungi and the presence or absence of nasal polyp and/or septal deviation.Fungal species had no effect on postoperative epithelialization.