Far-field super-resolution chemical microscopy

Far-feld chemical microscopy providing molecular electronic or vibrational fingerprint information opens a new window for the study of three-dimensional biological,material,and chemical systems.Chemical microscopy provides a nondestructive way of chemical identification without exterior labels.However,the diffraction limit of optics hindered it from discovering more details under the resolution limit.Recent development of super-resolution techniques gives enlightenment to open this door behind far-field chemical microscopy.Here,we review recent advances that have pushed the boundary of far-field chemical microscopy in terms of spatial resolution.We further highlight applications in biomedical research,material characterization,environmental study,cultural heritage conservation,and integrated chip inspection.