首荟通便胶囊联合复方聚乙二醇电解质散在慢性便秘患者行结肠镜检查前肠道准备中的效果观察

Observation on the efficacy of Shouhui Tongbian capsule combined with compound polyethylene glycol electrolyte powder in bowel preparation prior to colonoscopy in patients with chronic constipation

目的探讨首荟通便胶囊联合复方聚乙二醇电解质散在慢性便秘患者行结肠镜检查前肠道准备中的临床价值。方法选择2020年10月至2022年8月在该院行结肠镜检查的慢性便秘患者180例为研究对象,分为观察组和对照组,每组90例。结肠镜检查前对照组患者口服复方聚乙二醇电解质散,观察组患者口服复方聚乙二醇电解质散联合首荟通便胶囊。比较两组首次排便时间、肠道准备时间、回盲部插入时间、波士顿肠道评分量表(BBPS)评分、肠道气泡评分、肠道准备中的不良反应、肠道疾病检出情况。结果观察组患者肠道准备满意度和肠道气泡满意度明显高于对照组(P<0.01),首次排便时间、肠道准备时间、回盲部插入时间明显短于对照组(P<0.01),恶心呕吐、腹胀、心悸症状明显少于对照组(P<0.05),肠道息肉和腺瘤检出率明显高于对照组(P<0.05)。两组患者肠癌检出率比较差异无统计学意义(P>0.05)。结论首荟通便胶囊联合复方聚乙二醇电解质散在肠道准备中的效果优于单用复方聚乙二醇电解质散,结肠镜操作时间短,不良反应少,肠道疾病检出率高。

Objective To investigate the clinical efficacy of combining Shouhui Tongbian capsule with compound polyethylene glycol electrolyte powder for bowel preparation in patients with chronic constipation prior to colonoscopy.Methods A total of 180 patients with chronic constipation who underwent colonoscopy at our hospital from October 2020 to August 2022 were selected as the research subjects.They were randomly divided into the observation group and control group,with 90 cases in each group.Before the colonoscopy,the control group received compound polyethylene glycol electrolyte powder,while the observation group received a combination of compound polyethylene glycol electrolyte powder and Shouhui Tongbian capsule.The study compared several factors between the two groups,including the time of first defecation,bowel preparation time,ileocecal insertion time,Boston Bowel Scale(BBPS)score,intestinal bubble score,adverse reactions during colonoscopy,and detection of intestinal diseases.Results The satisfactions for intestinal preparation score and intestinal air bubble in the observation group were significantly better than those in the control group(P<0.01).The first defecation time,bowel preparation time,and ileocecal insertion time in the observation group were significantly shorter than those in the control group(P<0.01).The symptoms of nausea and vomiting,abdominal distension,and palpitation in the observation group were significantly less than those in the control group(P<0.05).The detection rates of intestinal polyps and adenomas in the observation group were significantly higher than those in the control group(P<0.05).There was no significant difference in the detection rate of colorectal cancer between the two groups(P>0.05).Conclusion The combination of Shouhui Tongbian capsule and compound polyethylene glycol electrolyte powder in intestinal preparation has a better effect than using compound polyethylene glycol electrolyte powder alone.The operation time for colonoscopy is shorter,the occurrence of adverse reactions is lower,and the detection rate of intestinal diseases is high.