中国2型糖尿病患者心理痛苦检出率的Meta分析

Detection rate of psychological distress among patients with type 2 diabetes mellitus in China:meta-analysis

目的系统评价我国2型糖尿病(T2DM)患者心理痛苦的检出状况。方法检索中国知网、维普、万方、中国生物医学文献数据库、美国国立医学图书馆数据库(PubMed)、荷兰医学文摘数据库(Embase)、科学引文数据库(Web of Science)从建库到2022年1月收录的所有关于T2DM患者心理痛苦检出率的文献。由2名研究人员根据纳入和排除标准独立筛选文献、提取资料并进行文献质量评价。采用Stata 14.0软件进行Meta分析,使用固定效应模型或随机效应模型进行数据合并,结合漏斗图、Egger检验评估发表偏倚。结果共纳入39篇文献,包括13348例研究对象。Meta分析结果显示,我国T2DM患者心理痛苦总检出率为54%(95%CI 45%~62%)。亚组分析显示,2012—2016年、2017年及以后心理痛苦检出率分别为51.7%(95%CI 42.2%~61.1%)和56.3%(95%CI 38.9%~73.6%),东部、中部、西部地区心理痛苦检出率分别为50.9%(95%CI 39.5%~62.3%)、55.9%(95%CI 53.9%~58.0%)和54.0%(95%CI 36.6%~71.3%),社区、住院患者心理痛苦检出率分别为54.7%(95%CI 40.6%~68.8%)和53.1%(95%CI 42.8%~63.4%),根据糖尿病痛苦量表、糖尿病问题量表-5的心理痛苦检出率分别为53.4%(95%CI 43.8%~63.0%)和50.4%(95%CI 39.6%~61.2%),轻中度、重度心理痛苦检出率分别为41.5%(95%CI 32.3%~50.7%)和13.4%(95%CI 10.6%~16.2%)。结论中国T2DM患者心理痛苦检出率较高,多数患者以轻中度心理痛苦为主。

Objective To systematically evaluate the pooled prevalence of psychological distress in patients with type 2 diabetes mellitus(T2DM)in China.Methods CNKI,VIP,WanFang Database,CBM,PubMed,Embase,Web of Science were searched to collect studies from inception to January 2022 for all literature on the detection rate of psychological distress in patients with T2DM.Two researchers independently screened literature,extracted information and evaluated the quality of the studies based on inclusion and exclusion criteria.We used Stata 14.0 software to evaluate the meta-analysis,and the data were combined using a fixed-effects model or a random-effects model,publication bias was detected using funnel plots and Egger′s tests.Results A total of 39 papers including 13348 study subjects were included.The pooled prevalence of psychological distress in Chinese patients with T2DM was 54%(95%CI 45%-62%).Subgroup analysis showed that the psychological distress detection rates were 51.7%(95%CI 42.2%-61.1%)in 2012—2016 and 56.3%(95%CI 38.9%-73.6%)in 2017 and beyond.The detection rates of psychological distress were 50.9%(95%CI 39.5%-62.3%),55.9%(95%CI 53.9%-58.0%),and 54.0%(95%CI 36.6%-71.3%)in the eastern,central,and western regions,respectively.The detection rates of psychological distress were 54.7%(95%CI 40.6%-68.8%)and 53.1%(95%CI 42.8%-63.4%)for community and inpatients.The detection rates of psychological distress according to the diabetes distress scale,and diabetes problem scale-5 were 53.4%(95%CI 43.8%-63.0%)and 50.4%(95%CI 39.6%-61.2%).The detection rates of mild to moderate and severe psychological distress were 41.5%(95%CI 32.3%-50.7%)and 13.4%(95%CI 10.6%-16.2%).Conclusions The detection rate of psychological distress in patients with T2DM in China is relatively high,and most of the patients have mild to moderate psychological distress.