遗传性口腔疾病相关牙齿替换障碍的早期治疗原则

Early treatment principles of tooth replacement disorders associated with hereditary oral diseases

牙齿替换障碍表现为乳牙脱落异常及恒牙萌出障碍。涉及多颗牙齿替换障碍的遗传性疾病主要包括颅骨锁骨发育不全、骨硬化症和加德纳综合征(Gardner syndrome)3种。这3种疾病较罕见,治疗难度大,治疗原则存在较大差异。本文以这3种遗传性疾病为例,阐述遗传性口腔疾病相关牙齿替换障碍的临床表现、早期治疗原则,以及口腔医师在多种遗传性疾病早期诊断中的重要作用。

Tooth replacement disorders are characterized by retention of deciduous teeth and abnormalities in permanent teeth eruption.Hereditary disorders with multiple teeth involved include cleidocranial dysplasia,osteopetrosis and Gardner syndrome.These rare diseases have great difficulty in treatment with various principles reported.This article focused on clinical manifestations and early treatment principles of these hereditary disorders,as well as the important role of dentists in early diagnosis of these diseases.