以椎管多发占位起病的髓系肉瘤1例

One case of myeloid sarcoma with multiple space occupying lesions in the spinal canal

髓系肉瘤是一种或多种髓系原始细胞在髓外增殖所形成的肿瘤性包块,多与急性髓系白血病(AML)相关。据报道,2.5%~9.1%的AML患者患有髓系肉瘤,其中,合并椎管髓系肉瘤罕见。椎管髓系肉瘤常起病急重,诊断较为困难,容易造成漏诊、误诊,从而导致确诊时间延迟,严重影响患者的救治和生活质量。现将北京协和医院血液科诊治的1例以椎管多发占位起病的髓系肉瘤患者的临床资料和诊治过程进行总结,以期为临床工作者提供参考。

Myeloid sarcoma(MS)is a tumor mass formed by the proliferation of one or more myeloid primitive cells outside the marrow,which is mostly related to acute myeloid leukemia(AML).It is reported that 2.5%to 9.1%of AML patients have MS,and AML with spinal canal MS is very rare.Spinal canal MS often has an acute onset and is difficult to diagnose.It is easy to cause missed diagnosis and misdiagnosis,which will lead to a delay in accurate diagnosis seriously affecting the treatment and quality of life among these patients.The clinical data,diagnosis and treatment process of a case of MS with multiple space occupying lesions in the spinal canal diagnosed and treated by the Department of Hematology of Peking Union Medical College Hospital are reported,in order to provide reference for clinical workers.