衰弱对老年患者手术后认知功能影响的研究进展

Research progress on the effects of frailty on postoperative cognitive function in elderly patients

衰弱是身体机能、认知、心理衰退的一种多维综合征。衰弱可增加机体对应激的易损性,并导致患者术后并发症增加、住院时间延长、甚至死亡率上升。随着人口老龄化进程不断加快,越来越多的老年患者需接受手术治疗,而该类患者手术后容易发生认知功能障碍。衰弱是老年患者常见的合并状态,但衰弱对老年患者手术后认知功能的影响尚未完全明确。本文就衰弱与老年患者术后谵妄、术后认知功能障碍及术后认知功能改善相关研究做出综述,为临床开展衰弱与术后认知研究提供参考。

Frailty is a multidimensional syndrome of physical functional,cognitive,and psychological decline.Frailty tends to increase the vulnerability to stress of the body,which leads to increased postoperative complications,prolonged hospital stay,and even higher mortality.Along with the accelerating process of aging in society,more and more elderly patients require surgical treatment.Such patients are prone to cognitive dysfunction after surgery.Frailty is a common comorbid state in elderly patients,but the effect of frailty on postoperative cognitive function in elderly patients has not been fully clarified.In this paper,we summarize the research on postoperative delirium,postoperative cognitive dysfunction and postoperative cognitive improvement in the elderly with frailty,providing ideas for clinical research on frailty and postoperative cognitive function.