多元复合声治疗对突聋患者耳鸣的疗效分析

Efficacy of compound sound therapy for patients with tinnitus and sudden deafness

目的探讨多元复合声治疗在突聋患者耳鸣的疗效,为突聋患者的耳鸣治疗提供参考。方法回顾性分析2017年1月至2020年8月收治的112例单侧突聋伴耳鸣患者的临床资料,其中58例采用多元复合声联合药物治疗为观察组,54例采用单独药物治疗为对照组。详细收集患者病例资料,并行纯音听阈测定、耳鸣测试,以及耳鸣残疾评估量表、视觉模拟量表和焦虑自评量表评分。对比两组患者治疗前后听力水平、耳鸣严重程度及负性情绪评分。结果治疗后两组患者听力总有效率显著提高,2周、1个月、3个月后听力总有效率观察组分别为55.2%、75.9%、77.6%,对照组为53.7%、77.8%、80.3%,组间差异无统计学意义(P>0.05)。治疗1个月、3个月后观察组耳鸣疗效(62.1%、81.1%)优于对照组(53.7%、59.3%),组间差异有统计学意义(P<0.05)。观察组耳鸣疗效在治疗3个月后(81.1%)优于治疗1个月后(62.1%),差异有统计学意义(P<0.05)。结论多元复合声治疗对突聋患者的耳鸣疗效显著,延长治疗时间可提高耳鸣疗效。

Objective The objectives of this study were to evaluate the efficacy of compound sound therapy and provide guidance for clinical practice for patients with tinnitus and sudden deafness.Methods We retrospectively analyzed clinical data from 112 patients with tinnitus and unilateral sudden deafness who were treated in our department between January 2017 and August 2020.Patients were randomly divided into two groups according to the treatment:54 patients in the control group were treated with medical therapy,and 58 patients in the observation group were treated with medical therapy in addition to compound sound therapy.Clinical data were collected for age,sex,laterality,and duration.All patients received the pure-tone audiometry and tinnitus tests,including loudness and residual inhibition.The Tinnitus Handicap Inventory,Visual Analogue Scale and Self-Rating Anxiety Scale scores were measured pre-and post-therapy.The compound sounds were remixed with noise/pure tone,natural sound,and music clips.The masking frequency of background sound was consistent with the tinnitus frequency of patients,and the main frequency of music clips covered the tinnitus frequency.Results The means of the pure tone hearing thresholds of the two groups after treatment were signif-icantly lower at 2 weeks,1 month,and 3 months after treatment.The total effective rates of hearing in the control group were 53.7%,77.8%,and 80.3%,and the rates in the observation group were 55.2%、75.9%、and 77.6%at 2 weeks,1 month,and 3 months,respectively.No significant difference was found between the two groups(P>0.05).The THI,VAS,and SAS scores significantly decreased after treatment in both groups,The total effective rates of tinnitus in the observation group were 62.1%and 81.1%,which were significantly better than those in the control group,which were 53.7%and 59.3%at 1 month and 3 months after treatment,respectively.The highest effect was observed in the observation group at 3 months after the compound sound therapy.This effect was better than at 1 month post-treatment,and the difference was statistically significant(all P<0.05).Conclusion Pa-tients with tinnitus and sudden deafness showed adaptations with compound sound therapy and acquired more benefits from extension of treatment duration.