摘要
As the most prevalent neurodevelopmental disorders in children,autism spectrum disorders(ASD)are characterized by deficits in language development,social interaction,and repetitive behaviors or inflexible interests.Contactin associated protein like 2(CNTNAP2),encoding a single transmembrane protein(CNTNAP2)with 1331 amino acid residues,is a widely validated ASD-susceptible gene.
基金
This work was supported by funding from National Natural Science Foundation of China(NSFC),Grant/Award Number:81770780 and 31972913
Key Research and Development Programs from Hunan Province,Grant/Award Number:2021DK2001
Guangdong Key Project in‘Development of New Tools for Diagnosis and Treatment of Autism’,Grant/Award Number:2018B030335001
Strategic Priority Research Program of Central South University,Grant/Award Number:ZLXD2017004
The project has been funded in part with Independent Exploration and Innovation Project of Central South University,Grant/Award Number:2018zzts393.