紫外光交联的胶原/纤维素气凝胶的制备及性能

Preparation and Characterization of Collagen-Carboxycellulose Composite Aerogel

生物质基气凝胶不仅具有传统气凝胶的优异性能,还保持了生物质出色的生物相容性、生物降解性和亲水性,具有广阔的应用前景。以酶解法制备的胶原蛋白(猪源)和羧基化纳米纤维素为原料(胶原蛋白∶羧基化纳米纤维素质量比为7∶3),利用清洁高效的紫外光(UV-365 nm)进行照射交联,成功制备了一种稳定多孔的三维气凝胶。重点研究了交联时间、交联方式对于胶原/纤维素气凝胶结构与性能的影响。从扫描电子显微镜图可以明显看出,纤维素在交联的胶原蛋白片层间形成搭接桥梁结构,有效提升了三维网络结构的稳定性。傅里叶变换红外光谱、热重分析及X射线衍射等分析手段证明短时间紫外照射(UV-2 h)可以有效提升胶原/纤维素气凝胶的性能,且不会对其微观结构产生破坏。紫外光照射交联的胶原/纤维素气凝胶表现出优异的物理特征,包括低体积密度(28.7 mg/cm3)、高孔隙率、机械稳定性(100次稳定循环)。

Biomass-based aerogels not only possess the exceptional characteristics of traditional aerogels,such as high porosity and a large specific surface area,but also maintain the outstanding biocompatibility,biodegradability,and hydrophilicity of biomass.This provides them with a wide range of opportunities for application.A stable and porous three-dimensional aerogel was successfully prepared using collagen and nanocellulose as raw materials.The mass ratio of collagen to nanocellulose was 7:3,and the crosslinking process was achieved using clean and efficient ultraviolet light(UV-365 nm)irradiation.The effects of crosslinking time and method on the structure and properties of collagen/cellulose aerogel were studied in detail.It is evident from the scanning electron microscope photos that cellulose forms an overlapping bridge structure between the cross-linked collagen layers.This structure significantly enhances the stability of the three-dimensional network structures.Short-term ultraviolet irradiation(UV-2 h)can effectively enhance the performance of collagen/cellulose aerogel without compromising its microstructure.This has been demonstrated through Fourier Transform Infrared Spectroscopy,Thermogravimetric Analysis and X-ray Diffraction.The functionalized aerogels exhibit superior physical characteristics,such as low density(bulk density of 28.7 mg/cm3),high porosity,and mechanical stability(100 cycles of stable circulation).