摘要
目的观察直肠超声双重造影及介入活检一体化检查用于直肠肿瘤定性诊断及恶性肿瘤分期诊断的临床效果。方法选取湖州市第一人民医院2019年12月至2022年3月收治的直肠肿瘤患者300例为研究对象,患者均行直肠超声双重造影及介入活检一体化检查并实施直肠肿瘤病灶切除术,以术后组织病理检查结果为金标准,分析直肠超声双重造影及介入活检一体化检查对直肠肿瘤定位、定性和恶性肿瘤分期的诊断效能。结果直肠超声双重造影及介入活检一体化检查对直肠肿瘤定位诊断符合率为100.0%,对直肠肿瘤定性诊断敏感性、特异性和准确性分别为94.8%、97.8%和96.7%,与术后组织病理检查对直肠肿瘤定性诊断一致性Kappa值为0.947,定性诊断直肠肿瘤的曲线下面积为0.974;直肠超声双重造影及介入活检一体化检查对Ⅰ~Ⅲ期直肠癌诊断的敏感性、特异性和准确性为94.1%~97.8%,与术后组织病理检查对Ⅰ~Ⅲ期直肠癌分期诊断一致性Kappa值分别为0.923、0.912和0.927,对直肠癌分期诊断的曲线下面积分别为0.961、0.955和0.970。结论直肠超声双重造影及介入活检一体化检查对直肠肿瘤定位、定性及分期诊断均具有较高诊断效能,可作为直肠肿瘤术前病情评估的有效工具。
Objective To investigate the clinical efficacy of qualitative and staging diagnosis of rectal tumors with dual contrast-enhanced ultrasonography and interventional biopsy.Methods A total of 300 patients with rectal tumors who received treatment in The First People's Hospital of Huzhou from December 2019 to March 2022 were included in this study.All patients underwent dual contrast-enhanced ultrasonography and interventional biopsy followed by focus resection.Taking the postoperative histopathological test results as the gold standard,the efficacy of dual contrast-enhanced ultrasonography and interventional biopsy in the localization,qualitative analysis,and staging of rectal tumors was analyzed.Results The compliance rate of dual contrast-enhanced ultrasonography and interventional biopsy in the localization of rectal tumors was 100%.The sensitivity,specificity,and accuracy of the dual contrast-enhanced ultrasonography and interventional biopsy for qualitative diagnosis of rectal tumors were 94.8%,97.8%,and 96.7%,respectively.The Kappa value used for assessing agreement in the qualitative diagnosis of rectal tumors between dual contrast-enhanced ultrasonography and interventional biopsy and postoperative tissue pathological examination results was 0.947.The area under the curve plotted for qualitative diagnosis of rectal tumors was 0.974.The sensitivity,specificity,and sensitivity of dual contrast-enhanced ultrasonography and interventional biopsy for diagnosis of stage I-III rectal cancer were 94.1%-97.8%.The Kappa values used for assessing agreement in staging diagnosis of stage I-III rectal cancer between dual contrast-enhanced ultrasonography and interventional biopsy and postoperative tissue pathological examination results were 0.923,0.912,and 0.927,respectively.The areas under the curve plotted for staging diagnosis of rectal cancer were 0.961,0.955,and 0.970,respectively.Conclusion Dual contrast-enhanced ultrasonography and interventional biopsy have a high efficacy in the localization,qualitative diagnosis,and staging diagnosis of rectal tumors.
作者
邓弼云
陆敏姣
陆文明
郭碧萍
Deng Biyun;Lu Minjiao;Lu Wenming;Guo Biping(Department of Ultrasound,The First People's Hospital of Huzhou,Huzhou 313000,Zhejiang Province,China)
出处
《中国基层医药》
CAS
2023年第8期1184-1188,共5页
Chinese Journal of Primary Medicine and Pharmacy
基金
浙江省医药卫生科技计划(2019PY015)。
关键词
直肠肿瘤
腔内超声检查
超声造影
介入诊断
活组织检查
诊断
敏感性与特异性
曲线下面积
Rectal neoplasms
Endosonography
Contrast-enhanced ultrasound
Interventional diagnosis
Biopsy
Diagnosis
Sensitivity and specificity
Area under curve