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氧化应激在病理性瘢痕中的研究进展

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摘要 病理性瘢痕是一种伤口异常愈合的皮肤纤维增生性疾病,其特征是真皮成纤维细胞过度增殖,导致过多胶原等细胞外基质成分沉积。病理性瘢痕会导致患者功能障碍、畸形和心理问题,但形成的机制尚未完全阐明。越来越多的证据显示,氧化应激在病理性瘢痕的发生发展中起着重要作用。概述氧化应激对病理性瘢痕形成的影响以及氧化应激与其他因素如炎症、凋亡、自噬共同影响病理性瘢痕形成的进展,以期为病理性瘢痕的防治提供新思路。
出处 《中华医学美学美容杂志》 2023年第4期331-334,共4页 Chinese Journal of Medical Aesthetics and Cosmetology
基金 新疆维吾尔自治区自然科学基金(2019D01C308)。
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