血清降钙素原检验在妇科感染性疾病治疗中的应用价值

Application value of serum calcitonogen test in the treatment of gynecological infectious diseases

目的探究血清降钙素原(PCT)检验在妇科感染性疾病治疗中的应用价值。方法选取2019年7月至2020年8月本院收治的50例妇科感染性疾病患者作为观察组,通过病原微生物分离培养将观察组分为细菌性感染组(n=33)、真菌性感染组(n=17);另选取本院同期体检健康女性50名作为对照组。比较两组治疗前后血清PCT水平及不同PCT阈值阳性检测率。结果治疗前,观察组PCT水平明显高于对照组,差异有统计学意义(P<0.05);治疗后,观察组PCT水平明显低于治疗前,但仍高于对照组,差异有统计学意义(P<0.05)。细菌性感染组PCT≥0.20μg/L和PCT≥0.50μg/L阳性检出率均明显高于真菌性感染组,差异有统计学意义(P<0.05);细菌性感染组PCT<0.20μg/L和PCT<0.50μg/L阳性检出率均明显低于真菌性感染组,差异有统计学意义(P<0.05);细菌性感染组PCT≥0.20μg/L阳性检出率明显高于PCT≥0.50μg/L,<0.20μg/L阳性检出率明显低于<0.50μg/L,差异有统计学意义(P<0.05)。结论血清降钙素原检验可为妇科感染性疾病临床治疗提供重要参考价值,有助于鉴别不同感染类型,反映患者受感染程度,值得临床推广应用。

Objective To explore the application value of procalcitonin(PCT)in the treatment of gynecological infectious diseases.Methods A total of 50 patients with gynecological infectious diseases admitted to our hospital from July 2019 to August 2020 were selected as the observation group,and the observation group was divided into the bacterial infection group(n=33)and the fungal infection group(n=17)through the isolation and cultivation of pathogenic microorganisms;in addition,50 healthy women in the same period were selected as the control group,the serum PCT levels before and after treatment and positive detection rates of different PCT thresholds were compared between the two groups.Results Before treatment,the PCT level in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the PCT level in the observation group was significantly lower than that before treatment,but still higher than that in the control group,the difference was statistically significant(P<0.05).The positive detection rates of PCT≥0.20μg/L and PCT≥0.50μg/L in bacterial infection group were significantly higher than those in fungal infection group,and the differences were statistically significant(P<0.05).The positive detection rates of PCT<0.20μg/L and PCT<0.50μg/L in bacterial infection group were significantly lower than those in fungal infection group,and the differences were statistically significant(P<0.05).The positive detection rate of PCT≥0.20μg/L in bacterial infection group was significantly higher than that of PCT≥0.50μg/L,and the positive detection rate of<0.20μg/L was significantly lower than that of<0.50μg/L,the differences were statistically significant(P<0.05).Conclusion The serum calcitonogen test can provide important reference value for the clinical treatment of gynecological infectious diseases,help to identify different types of infection,reflect the degree of infection of patients,and which is worthy of clinical promotion and application.