神经外科锁孔术治疗颅内肿瘤的临床疗效

The clinical efficacy of neurosurgical keyhole surgery in the treatment of intracranial tumors

目的探究神经外科锁孔术治疗颅内肿瘤的临床疗效。方法选取2017年11月至2019年11月本院收治的100例颅内肿瘤患者作为研究对象,根据手术方式不同分为对照组与实验组,每组50例。对照组行常规开颅术,实验组行经锁孔术,比较两组手术指标、临床疗效、术后并发症发生率及术后社会功能缺陷筛选量表(SDSS)评分、视觉模拟评分法(VAS)评分、生命质量指数(QLI)评分。结果实验组手术时间、手术切口长度均明显短于对照组,术中出血量少于对照组,差异有统计学意义(P<0.05)。实验组疾病控制率、客观缓解率分别为98.00%、88.00%,均高于对照组的78.00%、58.00%,差异有统计学意义(P<0.05)。实验组术后并发症发生率为14.00%,明显低于对照组的34.00%,差异有统计学意义(P<0.05)。实验组SDSS、VAS评分均明显低于对照组,QLI评分高于对照组,差异有统计学意义(P<0.05)。结论神经外科锁孔术治疗颅内肿瘤疗效显著,患者不良反应少,且可明显缩短手术时间,减少患者术中出血量,利于患者康复,值得临床推广应用。

Objective To investigate the clinical efficacy of neurosurgical keyhole surgery in the treatment of intracranial tumors.Methods A total of 100 patients with intracranial tumor admitted to our hospital from November 2017 to November 2019 were selected as the research subjects,and they were divided into the control group and the experimental group according to different surgical methods,with 50 cases in each group.The control group received conventional craniotomy,and the experimental group received keyhole surgery,the surgical indicators,clinical efficacy,postoperative complication rate,postoperative social disability screening schedule(SDSS)score,visual analog scale(VAS)score,and quality life index(QLI)score were compared between the two groups.Results The operation time and incision length in the experimental group were significantly shorter than those in the control group,and the intraoperative blood loss was less than that in the control group,the differences were statistically significant(P<0.05).The disease control rate and objective remission rate in the experimental group were 98.00%and 88.00%,respectively,which was higher than 78.00%and 58.00%in the control group,the differences were statistically significant(P<0.05).The incidence of postoperative complications in the experimental group was 14.00%,which was significantly lower than 34.00%in the control group,and the difference was statistically significant(P<0.05).The SDSS and VAS scores in the experimental group were significantly lower than those in the control group,and QLI scores was higher than that in the control group,the differences were statistically significant(P<0.05).Conclusion Neurosurgical keyhole surgery has significant efficacy in the treatment of intracranial tumors,less adverse reactions,and can significantly shorten the operation time,reduce intraoperative blood loss,conducive to the rehabilitation of patients,which is worthy of clinical promotion and application.