2014-2021年武汉市胰腺癌死亡率及流行趋势分析

Analysis of Mortality and Prevalence of Pancreatic Cancer in Wuhan from 2014 to 2021

目的探究2014-2021年武汉市胰腺癌死亡率及流行趋势,为胰腺癌防控制定相关措施。方法收集2014-2021年武汉市胰腺癌死亡原因监测资料,采用原卫生部指定的死因登记软件以及PASW 18软件进行统计学分析。结果①2014-2021年武汉市胰腺癌死亡数为5184人,死亡率呈逐渐上升趋势,其中男性死亡率均在50%以上,2016年起在60%以上;70岁以上者死亡率占50%;发病至死亡时间以1~3个月居多,在50%左右;首发症状为腹痛、黄疸,占80%以上;死亡中以城市较多,是农村的3倍左右,占70%以上,上述和同项目比较差异有统计学意义(P<0.05)。②经Logistic回归分析,2014-2021年武汉市胰腺癌死亡率呈上升趋势,其中男性、年龄>70岁、城市、腹痛黄疸、发病1~3个月是胰腺癌死亡流行趋势,也是危险因素(P<0.05)。结论武汉市胰腺癌死亡率呈上升趋势,应将男性、70岁以上、城市居民作为重点关注对象,要早期重视腹痛黄疸患者,早期做好胰腺癌防治工作。

Objective To explore the mortality and epidemic trend of pancreatic cancer in Wuhan from 2014 to 2021,in order to formulate relevant measures for the prevention and control of pancreatic cancer in Wuhan.Methods The mortality data of pancreatic cancer in Wuhan from 2014 to 2021 were collected,and the cause of death registration software designated by the former Ministry of Health and PASW 18 software were used to statistical analysis.Results From 2014 to 2021,the death number of pancreatic cancer was 5184,and the mortality rate was increasing gradually.Male mortality rate was over 50%and increased to 60%from 2016.The mortality rate of people over 70 years old was 50%.About 50%dead within 1-3 months from cancer onset.The first symptoms were abdo-minal pain and jaundice,accounting for more than 80%of deaths.Most of the dead were in occurred in cities,about three times as many as in rural areas.There was a significant difference between the above and the same items(P<0.05).Logistic regression analysis showed an upward trend of the mortality rate of pancreatic cancer in Wuhan city from 2014 to 2021.Male,age older than 70,citizen,abdominal pain jaundice and 1-3 months of onset were the risk factors of pancreatic cancer death(P<0.05).Conclusion The mortality rate of pancreatic cancer in Wuhan is increasing.We should pay more attention to men,over 70 years old,and urban residents.We should pay more attention to patients with abdominal pain and jaundice,and prevent pancreatic cancer as early as possible.