摘要
非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)是世界范围内最见的弥漫性肝病之一。约1/3的NAFLD会发展为非酒精性脂肪性肝炎,导致不同程度的肝纤维化或肝硬化,增加肝癌的患病风险。对NAFLD早期识别和分级评估,并进行积极干预,对延缓病程发展至关重要。肝穿刺活检是量化肝脂肪变性的金标准,但其为有创操作,且存在取样误差。超声检查具有简便、实时、无创等优势,被指南推荐为NAFLD首选的影像学诊断手段。本文综述近年来超声新技术在NAFLD诊断中的应用进展。
Non-alcoholic fatty liver disease(NAFLD)is one of the most common diffuse liver diseases worldwide.Approximately one-third of NAFLD will develop into non-alcoholic steatohepatitis,liver fibrosis,and even cirrhosis,and increasing the risk of liver cancer.Early diagnosis,grading and active intervention of NAFLD are essential to postpone the disease progression.The pathology of liver biopsy is the gold standard for quantifying steatosis of liver.However,it is an invasive operation with potential sampling errors.Ultrasound examination is recommended as the first line imaging diagnostic program for NAFLD by the guidelines,with the advantages of convenient,real time and non-invasive.This article reviewed the recent advances in the application of novel techniques based on ultrasound in the diagnosis of NAFLD.
作者
黄韵琳
董怡
HUANG Yunlin;DONG Yi(Department of Ultrasound,Xinhua Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China;Department of Ultrasound,Zhongshan Hospital,Fudan University,Shanghai 200032,China)
出处
《肿瘤影像学》
2023年第4期386-392,共7页
Oncoradiology
基金
国家自然科学基金(82071942)。
关键词
非酒精性脂肪性肝病
脂肪变性
超声
背向散射
声衰减系数
声速
Non-alcoholic fatty liver disease
Steatosis
Ultrasound
Backscatter
Attenuation coefficient
Sound speed
