肥胖症儿童肠道微生物组特征与治疗策略研究进展

Research progress on intestinal microbiome characteristics and treatment strategies of childhood obesity

儿童肥胖症是当前全球面临的公共健康问题,严重影响儿童的正常生长发育。近年来大量研究指出,肠道微生物组与儿童肥胖症关系密切,针对肠道微生物组的治疗策略对儿童肥胖症具有一定改善作用。该文对儿童微生物组的建立和发展、肥胖症儿童肠道微生物组特征、肠道微生物组参与儿童肥胖症发生发展的机制及潜在的干预策略进行了阐述,旨在为儿童肥胖症的基础及临床研究提供更多思路。

Childhood obesity is a global public health problem that seriously affects the normal growth and development of children.In recent years,a large number of studies have pointed out that the intestinal microbiome is closely related to childhood obesity,and the treatment strategies targeting the intestinal microbiome have a certain improvement effect on childhood obesity.This article elaborates on the establishment and development of intestinal microbiome,intestinal microbiome characteristics,the mechanisms of intestinal microbiome involvement in the occurrence and development of childhood obesity,and potential intervention strategies,so as to provide more ideas for basic and clinical research on childhood obesity.