支气管哮喘与慢性阻塞性肺疾病患者肺功能研究

Study of lung function of bronchial asthma and chronic obstructive pulmonary disease

目的比较支气管哮喘(哮喘)与慢性阻塞性肺疾病(慢阻肺)患者肺功能。方法回顾性分析2018年11月至2020年6月本院门诊和住院的60例哮喘患者(哮喘组)及60例慢阻肺患者(慢阻肺组)的肺功能资料,比较患者肺通气功能指标[第1秒用力呼气容积(FEV1)、用力肺活量(FVC)、最大呼气中段流量(MMF)、用力呼气50%肺活量的瞬时流量(FEF50%)、用力呼气75%肺活量的瞬时流量(FEF75%)]。结果哮喘组FEV1、FVC均大于慢阻肺组,差异有统计学意义(P<0.05)。哮喘组FEF50%、FEF75%、MMF均大于慢阻肺组,差异有统计学意义(P<0.05)。结论与哮喘患者比较,慢阻肺患者肺通气功能下降,小气道功能障碍明显,临床治疗需考虑上述因素。

Objective To compare the lung function of bronchial asthma(asthma)and chronic obstructive pulmonary disease(COPD).Methods The pulmonary function data of 60 asthma patients(asthma group)and 60 COPD patients(COPD group)in our hospital from November 2018 to June 2020 were retrospectively analyzed.The pulmonary ventilation function indexes(forced expiratory volume in one second[FEV1],forced vital capacity[FVC],maximum midexpiratory flow[MMF],forced expiratory flow at 50%of FVC[FEF50%],forced expiratory flow at 75%of FVC[FEF75%])were compared.Results FEV1,FVC in the asthma group was larger than that in the COPD group,and the difference was statistically significant(P<0.05).The FEF50%,FEF75%and MMF in the asthma group were higher than those in the COPD group,and the differences were statistically significant(P<0.05).Conclusion Compared with patients with asthma,patients with chronic obstructive pulmonary disease have decreased pulmonary ventilation function and obvious small airway dysfunction,these factors should be considered in clinical treatment.