兔正常肘管及尺神经解剖X线石蜡切片及电生理研究

Anatomy X-rays paraffin section and electrophysiology of normal cubital tunnel and ulnar nerve in rabbits

目的探讨建立兔肘管综合征模型的可行性。方法解剖5只6~8月龄成年新西兰雄性大白兔[济南金丰实验动物有限公司, 合格证号为SCXK(鲁)20180006], 研究正常肘管及尺神经的解剖, X线及石蜡切片表现, 在此基础上, 再对5只相同的新西兰雄性大白兔进行电生理研究, 得出10例尺神经传导速率, 利用计算算术平均数的方法得出兔正常尺神经的传导速率。结果新西兰雄性大白兔尺神经走形及支配清楚, 其肘管处无Osborne韧带腱性组织, 而是被肌肉组织替代, 此肌肉平均长度10 mm, 宽度8 mm, 厚度1 mm。兔尺神经沟发育明显, 并且肘管内形成一个三角形间隙使肘管的容积增大。肘管处尺神经平均直径1.5 mm, 石蜡切片可见尺神经纤维束及营养血管。尺神经传导速率平均(60.5±1.5) m/s。结论本研究推导出兔肘管综合征模型的建立在理论上具有可行性。

Objective To explore the feasibility of establishing a model of cubital tunnel syndrome in rabbits.Methods We dissected 56-8 months old adult New Zealand male rabbits to study the anato-my,X-rays and paraffin section of normal cubital tunnel and ulnar nerve.On this basis,electrophysiologi-cal studies were conducted on other 5 same rabbits and the normal ulnar nerve conduction rate was obtained by arithmetic mean.Results The ulnar nerve of male New Zealand white rabbits was similar to that of hu-man.The Osborne's ligament was replaced by muscle tissue in the cubital tunnel of male New Zealand white rabbits.This muscle has an average length of 10 mm,width of 8 mm and thickness of 1 mm.The ul-nar nerve groove developed obviously in rabbits,and a triangular gap formed in the cubital tunnel increased the volume of the cubital.The average diameter of the ulnar nerve at the cubital tunnel was 1.5 mm,and the paraffin section was similar to that of human.The average conduction velocity of the ulnar nerve was(60.5±1.5)m/s.Conclusion This study confirms that the establishment of cubital tunnel syndrome in rabbits is theoretically feasible.