吴以岭“络病”学说探讨溃疡性结肠炎“病证结合”的分期诊疗思路

WU Yiling's"collateral disease"theory guides the staged diagnosis and treatment of ulcerative colitis by"combining disease and syndrome"

中国工程院院士吴以岭提出“络病”学说,系统构建络病理论体系,研究内容针对各类难治性疾病的诊治,其诊疗模式具有疗效确切、不良反应少、安全持久的独特优势。溃疡性结肠炎作为全球难治性疾病之一,严重影响患者的生存质量,临床治疗原则是控制炎症、缓解症状、提高生活质量。近年来,中医药通过整体观念,进行个体化治疗溃疡性结肠炎取得了较为满意的临床疗效,而“络病”学说的提出,是对溃疡性结肠炎诊疗系统的进一步完善。本文聚焦于中医学“络病”理论研究,进行“病证结合”的诊疗方式沟通中西医桥梁,采取综合治疗手段。目的是建立溃疡性结肠炎的“络病”病证结合体系,及时有效辨别肠络损伤病变,指导UC疾病的分期诊疗及临床用药。

WU Yiling,an academician of the CAE Member,put forward the theory of"collateral disease",and systematically constructed the theoretical system of collateral disease.The research content is aimed at the diagnosis and treatment of various refractory diseases.Its diagnosis and treatment mode has unique advantages of accurate efficacy,less adverse reactions,and safety and durability.Ulcerative colitis(UC),as one of the global refractory diseases,seriously affects the quality of life of patients.The clinical treatment principle is to control inflammation,alleviate symptoms and improve the quality of life.In recent years,Chinese medicine has achieved satisfactory clinical efficacy in individualized treatment of UC through the overall concept,and the"collateral disease"theory is to further improve the diagnosis and treatment system of UC.This article focuses on the theoretical research of"collateral disease"in Traditional Chinese Medicine,and carries out the diagnosis and treatment of"disease syndrome combination"to communicate the bridge between Traditional Chinese Medicine and Western medicine,and adopt comprehensive treatment methods.The objective is to establish a disease syndrome combination system of"collateral disease"in UC,to timely and effectively identify the lesions of intestinal collateral injury,and to guide the staged diagnosis and treatment of UC and clinical medication.