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A Rapid and Accurate CRISPR/Cas12b-Mediated Genotyping Assay for the Methylenetetrahydrofolate Reductase Gene Polymorphism C677T

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摘要 Human methylenetetrahydrofolate reductase(MTHFR),an essential enzyme in folate metabolism,catalyzes the conversion of5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate.Several polymorphisms in the MTHFR gene have been found to be associated with reduced enzyme activity and related to folic acid intake in relevant populations[1].
出处 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2023年第6期561-565,共5页 生物医学与环境科学(英文版)
基金 supported by A Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD) the Open-End Funds of the Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening[HY202105]。
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