揿针疗法对冠心病经皮冠脉介入术后不稳定型心绞痛气虚血瘀证患者临床症状及炎症因子的影响

Effect of thumbtack needling therapy on clinical symptoms and inflammatory factors of unstable angina pectoris with syndrome of blood stasis due to qi deficiency in patients with coronary heart disease after percutaneous coronary intervention

目的探讨揿针疗法对冠心病经皮冠脉介入术(PCI)后不稳定型心绞痛气虚血瘀证患者临床症状及炎症因子的影响。方法依据随机数字表法将河北省唐山市中医医院2021年3月至2022年3月收治的冠心病PCI后不稳定型心绞痛气虚血瘀证患者112例分为对照组(56例)和研究组(56例),其中对照组采用常规治疗,研究组采用常规治疗及揿针疗法,两组均治疗1个月。比较两组疗效及治疗前后中医证候评分、炎症因子水平的差异,记录两组不良事件发生情况。结果研究组临床疗效优于对照组,差异有统计学意义(P<0.05)。治疗后,两组心胸刺痛、胸部憋闷、气短、乏力、心悸、面色苍白、倦怠评分均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。治疗后,两组血清超敏C反应蛋白、人软骨糖蛋白、白细胞介素-6水平低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。两组在治疗期间均未发生严重不良事件。结论揿针疗法可有效改善冠心病PCI后不稳定型心绞痛气虚血瘀证患者的临床症状,降低炎症因子水平,安全性较高。

Objective To investigate the effect of thumbtack needling therapy on clinical symptoms and inflammatory factors in unstable angina pectoris with syndrome of blood stasis due to qi deficiency in patients with coronary heart disease after percutaneous coronary intervention(PCI).Methods According to the random number table method,112 unstable angina pectoris patients with syndrome of blood stasis due to qi deficiency with coronary heart disease after PCI in Tangshan Traditional Chinese Medicine Hospital in Hebei Province from March 2021 to March 2022 were divided into control group(56 cases)and study group(56 cases).The control group was treated with routine treatment,and the study group was treated with routine treatment and thumbtack needling therapy.Both two groups were treated for one month.The curative effect was compared between the two groups,and the traditional Chinese medicine syndrome score,inflammatory factor levels were compared between the two groups before and after treatment,and the occurrence of adverse events was recorded.Results The clinical efficacy of the study group was better than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the scores of chest stabbing pain,chest distress,shortness of breath,malaise,palpitations,pale complexion,and burnout in the two groups were lower than those before treatment,and those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of serum high-sensitivity C-reactive protein,human cartilage glycoprotein,and interleukin-6 in the two groups were lower than those before treatment,and those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).No serious adverse events occurred in the two groups during the treatment.Conclusion The thumbtack needling therapy can effectively improve the clinical symptoms of unstable angina pectoris with syndrome of blood stasis due to qi deficiency in patients with coronary heart disease after PCI,reduce the levels of inflammatory factors,and has high safety.