人乳头瘤病毒、液基薄层细胞检测联合阴道镜检查在早期宫颈病变筛查中的意义

Significance of Human Papillomavirus,Liquid-Based Thin-Layer Cytology Detection Combined with Colposcopy in Early Cervical Lesion Screening

目的:探讨早期宫颈病变筛查中人乳头瘤病毒(HPV)、液基薄层细胞检测(TCT)联合阴道镜检查的意义。方法:选取2022年1—12月在南京市江宁区妇幼保健计划生育服务中心接受早期宫颈病变筛查的102例患者作为研究对象,患者均进行HPV、TCT及阴道镜检查,比较HPV、TCT、阴道镜及三者联合检查诊断早期宫颈病变的结果及效能。结果:HPV诊断早期宫颈病变阳性率为47.06%(8/17),TCT为58.82%(10/17),阴道镜为58.82%(10/17),三者联合检查为94.12%(16/17)。三者联合检查诊断早期宫颈病变的特异度、灵敏度、阳性预测值、阴性预测值均高于HPV、TCT、阴道镜单独检查。结论:联合应用HPV、TCT与阴道镜检查,可提高早期宫颈病变的诊断效能。

Objective:To explore the significance of human papillomavirus(HPV),liquid-based thin-layer cytology(TCT)detection combined with colposcopy in early cervical lesion screening.Methods:A total of 102 patients who received early cervical lesion screening in Nanjing Jiangning District Maternal and Child Health and Family Planning Service Center from January 2022 to December 2022 were included in this study.All patients received HPV,TCT and colposcopy.The results and efficacy of HPV,TCT,colposcopy and the combination of TCT,HPV and colposcopy in the screening of early cervical lesions were compared.Results:The positive rates of HPV,TCT,colposcopy and the combined examination in the diagnosis of early cervical lesions were 47.06%(8/17),58.82%(10/17),58.82%(10/17)and 94.12%(16/17),respectively.The specificity,sensitivity,positive predictive value,and negative predictive value of the combined examination in the diagnosis of early cervical lesions were higher than those of HPV,TCT,colposcopy alone.Conclusion:The combination of HPV,TCT and colposcopy can improve the diagnostic efficacy of early cervical lesions.