儿童自身免疫性脑炎研究进展

Research progress in autoimmune encephalitis in children

近年来,自身免疫性脑炎在中枢免疫性疾病中越来越受到重视,20世纪60年代,一些学者发现边缘受损患者通常合并其他系统肿瘤性病变,随着进一步深入研究,副肿瘤性、非副肿瘤性、感染性类型也被发现。关于自身免疫性脑炎的发病机制不明,临床上其最常见的分类依据是根据不同的抗受体类型进行分类,其临床表现根据分类不同而表现不一。对于不同临床症状,自身免疫性脑炎的治疗方案包括对症治疗及免疫治疗等。本文将通过对以上方面进行综述,以期为临床医生对此病的认识提供一定参考。

In recent years,autoimmune encephalitis has been paid more and more attention to in central immune diseases.In 1960s,some scholars have found that patients with marginal damage were often complicated with tumor lesions of other systems.With the research deepened,paraneoplastic,non-paraneoplastic and infectious types have also been found.The pathogenesis of autoimmune encephalitis is unknown.The most common clinical classification of autoimmune encephalitis is based on different types of antireceptors,and different classifications have different clinical manifestations.For different clinical symptoms,the treatment for autoimmune encephalitis includes symptomatic treatment and immunotherapy.This article will summarize the above aspects in order to provide some reference for clinicians'understanding of the disease.