苗药紫藤根化学成分的研究

Research on the Chemical Ingredients of Miao Medicine Wisteria sinensis(Sims)Sweet.

对紫藤(Wisteria sinensis(Sims)Sweet.)根的化学成分进行分离,通过硅胶、ODS、凝胶柱色谱及HPLC制备色谱等分离方法对紫藤根的乙酸乙酯部位及水部位进行了化学成分分离,通过HPLC、1HNMR(600MHz,DMSO-d6)、13CNMR(150MHz,DMSO-d6)等方法确认所得单体化学结构,分离得到6个化合物单体,分别为鸢尾苷(1)、鸢尾黄素7-O-β-D-(6”-O-乙酰基)-葡萄糖苷、芒柄花苷、紫藤苷、biochaninA7-O-glucoside、7-O-(6”-O-acetyl-β-D-glucopyranosyl)-6,4’-dimethoxy-5-hydroxyflavone。其中化合物6为首次从紫藤药材中分离得到。

Separate the chemical composition of Wisteria sinensis(Sims)Sweet root,Separate and water areas and water parts of Wisteria sinensis(Sims)Sweet root are separated by Silicone,ODS,gel column chromatography and HPLC chromatography and other separation methods,Confirm the obtained chemical structure obtained through methods such as HPLC,1H NMR(600 MHz,DMSO-D6),13C NMR(150 MHz,DMSO-D6)and other methods,Separate 6 compound monomers,they are tectoridin,tectorigenin-7-O-β-D-(6’’-O-acetyl)-glucoside,ononin,wistin,biochanin A 7-O-glucoside,7-O-(6”-O-acetyl-β-D-glucopyranosyl)-6,4’-dimethoxy-5-hydroxy flavone.Compound 6 was isolated from W.sinensis for the first time.