肝性骨营养不良临床研究进展

Progress of Clinical Research on Hepatic Osteodystrophy

肝性骨营养不良是慢性肝病尤其是肝硬化患者常见的骨骼系统并发症,产生骨软化和骨质疏松,表现为骨量减少,骨折易感性增加。多数情况下,该病的症状并不明显,如干预不及时易导致骨折,严重影响患者的生命质量。本文对肝性骨营养不良的病因、发病机制、诊断、治疗与预防等方面的研究现状作一简要综述。

Hepatic osteodystrophy is a common bone system complication in patients with chronic liver disease,especially liver cirrhosis.The manifestation is the occurrence of osteomalacia and osteoporosis,which is characterized by reduced bone mass and increased susceptibility to fracture.The symptoms are not obvious in most cases.If the intervention is not given timely,it is easy to have fracture and seriously affects the quality of life of patients.This paper briefly summarized the research status on the etiology,pathogenesis,diagnosis,treatment and prevention of hepatic osteodystrophy,in order to improve the understanding and attention of clinicians on this kind of disease.