冠脉内旋磨术治疗稳定性心绞痛前降支钙化病变的临床预后研究

Clinical Prognostic Study on the Treatment of Calcified Lesions in the An⁃terior Descending Branches of Stable Angina Pectoris by Intracoronary Rotary Milling

目的 探讨冠脉内旋磨术治疗稳定性心绞痛前降支钙化病变的临床预后效果。方法 选取2022年3月-2023年3月茂名市人民医院收治的100例稳定性心绞痛前降支钙化病变患者为研究对象,按照随机数表法将其分为观察组与对照组,各50例。对照组给予球囊扩张+支架植入术治疗,观察组在对照基础上进行冠脉内旋磨术治疗。比较两组手术前后病变情况、心功能指标,手术时间及住院时间,并发症总发生率。结果 术后,与对照组相比,观察组的最小管腔直径显著更大,病变最重狭窄率显著更低,左室射血分数更高,左心室舒张末径更窄,差异有统计学意义(P<0.05)。与对照组相比,观察组手术时间更长,住院时间更短,差异有统计学意义(P<0.05)。观察组并发症总发生率(2.00%)显著低于对照组的16.00%,差异有统计学意义(χ^(2)=4.396,P<0.05)。结论 冠脉内旋磨术治疗稳定性心绞痛前降支钙化病变可明显改善后患者的病变状况,提高患者的心功能指标、降低并发症的发生,利于预后。

Objective To investigate the clinical prognostic effect of intracoronary rotary milling for the treatment of calcified lesions of anterior descending branches in stable angina pectoris.Methods From March 2022 to March 2023,100 patients with calcified lesions in the anterior descending branch of stable angina pectoris admitted to Maom⁃ing People´s Hospital were selected as the research object and divided into an observation group and a control group according to the random number table method,with 50 cases in each group.The control group was treated with bal⁃loon dilation and stent implantation,while the observation group was treated with intracoronary rotational milling on the basis of the control group.Compared the pathological changes,cardiac function indicators,surgical time and hospi⁃tal stay,and total incidence of complications between the two groups before and after surgery.Results After surgery,compared with the control group,the smallest lumen diameter of the observation group was significantly larger,the most severe stenosis rate was significantly lower,the left ventricular ejection fraction was higher,and the left ventricu⁃lar end diastolic diameter was narrower,the difference was statistically significant(P<0.05).Compared with the con⁃trol group,the observation group had a longer surgical time and shorter hospital stay,the difference was statistically significant(P<0.05).The total incidence of complications in the observation group(2.00%)was significantly lower than that in the control group(16.00%),the difference was statistically significant(χ^(2)=4.396,P<0.05).Conclusion Intracoronary rotary milling for the treatment of calcified lesions in the anterior descending branches of stable angina pectoris can significantly improve the lesion status of patients,improve the cardiac function indexes of patients,re⁃duce the occurrence of complications,and benefit the prognosis.