摘要
Loss of neurons and disruption of neural circuits are associated with many neurological diseases,including neurodegenerative diseases and mental disorders.The most prevalent pathological feature of neurodegenerative diseases is the aggregate loss of certain neuronal populations.For example,the loss of dopamine(DA)neurons in the substantia nigra pars compacta has been defined as a pathological hallmark of Parkinson’s disease(PD;Kamath et al.,2022).
基金
supported by the National Natural Science Foundation of China,No.81971133
Liaoning Key Research and Development Project,No.2021JH2/10300059
Liaoning Revitalization Talents Prograrn,No.XLYC2002109(all to GL)。
